Rhinocort Inhaler – for what diseases it is used. Benefits of using budesonide by inhalation. When transferring patients to therapy with the Rhinocort inhaler from other inhalers, the treatment regimen should be selected individually.
Anti-inflammatories
NSAIDs are very widely used in almost all the departments of medicine. By some estimates, each year in the world more than 60 million prescriptions of non-aspirin NSAIDs are being produced. However, the actual number of patients taking NSAIDs is much more, since this medication is approved for use as a non-prescription medicines.
The action of NSAIDs at the cellular level is associated with the inhibition of the enzyme cyclooxygenase-2 (COX-2), which leads to disruption of the synthesis of prostaglandins (PG) – proinflammatory cytokines.
Anti-inflammatory effect is manifested at weakening stage of exudation (edema) and proliferation (proliferation of connective tissue). Violation of PG synthesis leads to a decrease of the selection of biologically active substances that activate inflammation (histamine, serotonin), increase membrane permeability and increase swelling. Reduction of edema happens due to the normalization of the vascular permeability of membranes during inflammation. Important role in the anti-inflammatory effect of NSAIDs is played by their antioxidants whose main property is to inhibit lipid peroxidation (LPO), the products of which are the free radicals that damage biological membranestion, therefore contributing to the progression of inflammation.
NSAIDs have a broad spectrum of side effects, including the three major groups: NSAID-induced gastropathy, drug damaged articular cartilage, and cardiovascular complications. The greatest number of side effects is associated with disorders of the gastrointestinal tract. Minimal (but not eliminated) risk of side effects on the gastrointestinal tract is caused by preferential and selective COX-2 blockers, which requires a combination of them with a proton pump blockers (omeprazole and others).
Prelone (Prednisolone)
Prelone is a synthetic oral medication that resembles cortisol in its action, with the only difference that cortisol occurs naturally in the body, and Prelone is a man-made substance. On the one hand, the medicine is meant to suppress the immune system and, on the other hand, is called to reduce inflammation linked to conditions such as Crohn’s disease, asthma, psoriasis, and even leukemia.
Azulfidine
Azulfidine is a medication that has anti-inflammatory and anti-microbial qualities. It is a mixture of 5-aminosalicylic acid and sulfapiridin. The medication is absorbed in small amounts from the colon’s lumen and then evenly distributed within the connective tissue.
Feldene
The nonsteroidal anti-inflammatory medication Feldene is prescribed to relieve the symptoms of osteoarthritis (OA) and reduce the symptoms of rheumatoid arthritis (RA).
Estrace
The female hormone estrogen is required for numerous bodily functions. In females, the daily production of estradiol by the ovaries can range from 70 to 500 micrograms. Estrone and, to a lesser extent, estriol are produced from this. Estrone is the most active circulating estrogen after menopause.